Abstract
An overview is presented of major methods used in combined treatment of depressive states in the course of affective disorders and schizophrenia: namely, I and II generation antidepressants may be combined with neuroleptics, anxiolytics, lithium carbonate, and anticonvulsant drugs. The most important indications to the combined treatment as well as its limitations are discussed. Main interactions between the above mentioned groups of drugs are outlined, with the emphasis on the risk of dangerous sequelae of come combinations of psychotropic drugs.