Abstract
The CNS development at the cellular level is outlined and findings of neuroimaging and pathomorphological studies of the CNS in schizophrenic patients are discussed in the paper. Brain structure abnormalities noted in schizophrenia seem to be determined by disorders in the process of the CNS formation, especially of the migration stage of cells eventually forming the temporal lobe and frontal cortex structures. Presented data underpin the concept of neurodevelopmental determinants of some types of schizophrenia.