2004 issue 3

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Volume 13, issue 3

Original article

Temperamental traits assessed by PTS (Pavlovian Temperamental Survey) and TCI (Temperament and Character Inventory) as predictors of pharmacotherapy effectiveness

Iwona Koszewska1, EWA PRAGŁOWSKA1, STANISŁAW PUŻYŃSKI1, ELŻBIETA BURNA-DRASKOVIC1, Marek Dąbrowski1, SŁAWOMIR FORNAL1, Antoni Kalinowski1, Łukasz Święcicki1, Jarosław Torbiński1
1. II Klinika Psychiatryczna Instytutu Psychiatrii i Neurologii w Warszawie
Postępy Psychiatrii i Neurologii, 2004, 13 (3), 215-224
Keywords: temperament, TCI, PTS, response to antidepressants

Abstract

Background. The goal of the study was to investigate temperamental traits as predictors of response to antidepressant treatment in major depression, in relationship with some clinical factors.

Method. 42 patients (24 women and 18 men) diagnosed with major depression were examined using the PTS and TCI temperament inventories.

Results. Patients with depression in the course of affective disorder who had a history of drug resistance and did not respond to the antidepressant treatment differed significantly from those with no drug resistance in the past and a positive response to the present treatment. The differences pertained to: harm avoidance, cooperativeness, persistence, and self-directedness on the TCI, as well as reactivity, repressiveness and mobility of the nervous system on the PTS.

Address for correspondence:
Dr Iwona Koszewska,
II Klinika Psychiatryczna Instytutu Psychiatrii i Neurologii,
ul. Sobieskiego 9,
02-957 Warszawa