Abstract
Background. The goal of the study was to investigate temperamental traits as predictors of response to antidepressant treatment in major depression, in relationship with some clinical factors.
Method. 42 patients (24 women and 18 men) diagnosed with major depression were examined using the PTS and TCI temperament inventories.
Results. Patients with depression in the course of affective disorder who had a history of drug resistance and did not respond to the antidepressant treatment differed significantly from those with no drug resistance in the past and a positive response to the present treatment. The differences pertained to: harm avoidance, cooperativeness, persistence, and self-directedness on the TCI, as well as reactivity, repressiveness and mobility of the nervous system on the PTS.