An overview of the literature on the treatment of brain stroke is presented. Despite numerous clinical studies, no drug has been found so far to be effective. The only confirmed efficient treatment method has been to provide the patient with appropriate care in a specialistic ward possibly soon, which allows to start his rehabilitation early and to undertake early treatment of general systemic disorders. Prevention, i.e. treatment reducing the effect of risk factors on brain stroke incidence is of crucial importance. The reduction of BS morbidity and mortality in highly industrialized countries is due mostly to an early diagnosis and appropriate treatment of hypertension, to change of lifestyle, healthy diet, and administration of antithrombotic and antiaggregating drugs both in the primary and secondary prevention.