1995 issue 4

Back

Volume 4, issue 4

Diagnostyka obrazowa i neuropsychologiczna

Cognitive functions in patients with bipolar affective disorder in remission and results of MRI investigation of the CNS

EWA HABRAT1, MARIA BERĘSEWICZ1, Iwona Koszewska1, TERESA KRYST-WIDŹGOWSKA2, Renata Poniatowska2
1. I Kliniki Psychiatrycznej IPiN w Warszawie
2. Zakładu Neuroradiologii IPiN w Warszawie
Postępy w Psychiatrii i Neurologii, 1995, 4, 409-417
Keywords: bipolar affective disorder, MRI, cognitive functions

Abstract

40 patients (22 males and 18 females) with bipolar affective disorder in remission were assessed using the Halstead-Reitan Neuropsychological Test Battery. Their test performance was related to the MRI brain image. The patients under study had difficulty with problem-solving tasks, impaired interhemispheric transfer (particularly male patients), decreased motor skill of the dominant hand, and reduced strength of grip in both hands. No relationship was found between the patients' scores on the Halstead-Reitan Battery and their brain image obtained by MRI. On the other hand, patients with low scores differed from those scoring within or above the normal range on the Tactile Recognition and Tapping tests, in the structure of the left temporal lobe (wider left temporal lobe, thicker cortex of the parahippocampal gyrus, and wider Sylvian fissure), as well as of the right temporal lobe (widening of the temporal horn of the lateral ventricles, widened Sylvian fissure); moreover, both their right amygdala nucleus and the surface of the corpus callosum were smaller.

Address for correspondence:
Mgr Ewa Habrat,
II Klinika Psychiatryczna IPiN,
Al. Sobieskiego 1/9,
02-957Warszawa