1996 suplement 1


Volume 5, suplement 1

Original article

Combined treatment of depression and affective disorders

1. I Kliniki Psychiatrycznej IPiN w Warszawie
Postępy Psychiatrii i Neurologii, 1996, 5, suplement 1 (3), 85-92
Keywords: depressions, affective disorders, I and II generation antidepressant drugs, neuroleptics, anxiolytics, normothymic drugs, monotherapy and combined treatment, drug interactions


An overview is presented of major methods used in combined treatment of depressive states in the course of affective disorders and schizophrenia: namely, I and II generation antidepressants may be combined with neuroleptics, anxiolytics, lithium carbonate, and anticonvulsant drugs. The most important indications to the combined treatment as well as its limitations are discussed. Main interactions between the above mentioned groups of drugs are outlined, with the emphasis on the risk of dangerous sequelae of come combinations of psychotropic drugs.

Address for correspondence:
Prof. Stanisław Pużyński,
Instytut Psychiatrii i Neurologii,
Al. Sobieskiego 1/9,02-957 Warszawa