1997 issue 1

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Volume 6, issue 1

Varia

The role of the tumor necrosis factor alpha (TNF-alpha) in the pathogenesis of multiple sclerosis

ANITA GEPPERT1, Jacek Losy1
1. Katedry i Kliniki Neurologii AM w Poznaniu
Postępy Psychiatrii i Neurologii, 1997, 6, 73-77
Keywords: TNF-alpha, multiple sclerosis

Abstract

Numerous data suggest that cytokines play an important role in the multiple sclerosis pathophysiology, both through regulation of inappropriate immunological reactions and through mediation in myelin damage. The TNF-alpha, as one of the main mediators of the inflammatory reaction, plays and important role in the pathogenesis of multiple sclerosis. The role of TNF-alpha in the multiple sclerosis is discussed in the paper.

Address for correspondence:
Dr Anita Geppert,
Katedra i Klinika Neurologii AM,
ul. Przybyszewskiego 49,
60-355 Poznań