1998 issue 1


Volume 7, issue 1

Ból i jego znaczenie

The pathophysiology of pain

1. Wojskowego Instytutu Higieny i Epidemiologii w Warszawie
Postępy Psychiatrii i Neurologii, 1998, 7, 19-29
Keywords: pain, pathophysiology


After presentation of the definition of pain, the authors discuss the pathways of nociceptive impulses and their stages: peripheral neurons, spinal neurons, and ascending pathways to thalamic nuclei. The nociceptive information undergoes modulation at various levels of pain pathways. The mechanisms modifying the sensation of pain or exerting antinociceptive action are various, and it is known presently, that a major role is played in it, apart from spinal factors, also descending pathways in the central nervous system. (Ed.)

Address for correspondence:
Dr Marek Kowalczyk, Wojskowy Instytut Higieny i Epidemiologii w Warszawie
ul. Kozielska 4, 01-163 Warszawa