1999 issue 1

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Volume 8, issue 1

Choroby infekcyjne o.u.n.

The Creutzfeldt-Jakob disease – epidemiological and clinical problems

Jerzy Kulczycki1
1. I Klinika Neurologiczna Instytutu Psychiatrii i Neurologii w Warszawie
Postępy Psychiatrii i Neurologii, 1999, 8, 5-14
Keywords: Creutzfeldt-Jakob disease, diagnosis, pathogenesis

Abstract

Currently accepted diagnostic criteriafor the Creutzfeldt-Jakob disease are presented.The prion theory of the disease pathogenesis isoutlined and essential data on its epidemiology aregiven. Attention is drawn to some recently obtainedevidence of the "mad cows' disease" effecton the emergence of a new form of human spongyencephalopathy. Clinical characteristics of the diseaseare discussed.

Address for correspondence:
Prof. Jerzy Kulczycki, I Klinika Neurologiczna IPiN, Al. Sobieskiego 1/9, 02-957 Warszawa