On the grounds of hitherto existing research findings an attempt was made in this paper to answer the question: what factors affect self-assessed quality of life in schizophrenic patients. The definition of quality of life and major scales measuring the construct were briefly presented. Analyzed factors were divided into several groups: those related to health status, to treatment received, and to socio-demographic characteristics. Reported research findings are not quite univocal. However, some regularities seem to emerge suggesting that a high quality of life can be attained in schizophrenic patients due to a number of factors: early treatment of the disorder, reduction of psychotic symptoms – especially negative ones, treatment of concurrent depressive and anxiety disorders, administration of atypical neuroleptics, shortening of the hospitalisation time, providing social support, rehabilitation and educational programs, as well as maintaining therapeutic relationship with the patient.