2004 issue 4

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Volume 13, issue 4

Review article

Hyperprolactinemia in schizophrenic patients treated with antipsychotics

ANNA WYSZOGRODZKA-KUCHARSKA1, Jolanta Rabe-Jabłońska1
1. Kliniki Chorób Afektywnych i Psychiatrii Młodzieżowej Uniwersytetu Medycznego w Łodzi
Postępy Psychiatrii i Neurologii, 2004, 13 (4), 355-362
Keywords: hyperprolactinemia, antipsychotic therapy, schizophrenia

Abstract

Aim. This review article deals with the current opinions on the role of prolactin and its secretion mechanism.

Review. We discuss the pathogenesis, clinical findings and long-term consequences of hyperprolactinemia and emphasize the mechanism of antipsychotics action. Both typical and some new atypical antipsychotics may influence the secretion of prolactin.

Conclusions. Using antipsychotics, it is necessary to recognize their influence on the prolactin secretion and hormones produced by the hypothalamus-pituitary-gonads axis.

Address for correspondence:
Dr Anna Wyszogrodzka-Kucharska,
Klinika Chorób Afektywnych i Psychiatrii Młodzieżowej Uniwersytetu Medycznego,
ul. Czechosłowacka 8/10,
92-216 Łódź,
e-mail: anakuch@poczta.onet.pl