2004 issue 4


Volume 13, issue 4

Case report

Paranoid psychosis as the first symptom of sporadic Creutzfeldt-Jakob disease

MARCIN WOLTERA1, Iwona Kłoszewska1, Paweł P. Liberski2, BEATA SIKORSKA2, Tomasz Sobów1
1. Klinika Psychiatrii Wieku Podeszłego i Zaburzeń Psychotycznych Uniwersytetu Medycznego w Łodzi
2. Zakładu Patologii Molekularnej i Neuropatologii Uniwersytetu Medycznego w Łodzi
Postępy Psychiatrii i Neurologii, 2004, 13 (4), 399-404
Keywords: sCJD, psychosis, dementia, parkinsonism


Aim. Sporadic CJD is diagnosed four times more often in western countries than in Poland. A typical clinical presentation consists of three symptoms: dementia, myoclonus and specific EEG picture. Some patients present psychiatric prodromal signs such as depressive disorders, personality changes, and emotional lability. Cases of sCJD, which begin with psychotic signs, are thought to be rare.

Case. A 68 year old man, who presented psychotic symptoms as onset of sCJD.

Comment. Intravital diagnosis of sCJD can be given in a non-typical case, only if the patient is thoroughly examined and we take into consideration psychiatric and cognitive disturbances other than those which are typical for elderly patients. sCJD should always be considered when dementia signs worsen rapidly alongside with neurological and psychotic symptoms.

Address for correspondence:
Dr Tomasz Sobów,
Klinika Psychiatrii Wieku Podeszłego i Zaburzeń Psychotycznych
Uniwersytetu Medycznego,
ul. Czechosłowacka 8/10,
e-mail: tmsobow@csk.am.lodz.pl