Aim. Sporadic CJD is diagnosed four times more often in western countries than in Poland. A typical clinical presentation consists of three symptoms: dementia, myoclonus and specific EEG picture. Some patients present psychiatric prodromal signs such as depressive disorders, personality changes, and emotional lability. Cases of sCJD, which begin with psychotic signs, are thought to be rare.
Case. A 68 year old man, who presented psychotic symptoms as onset of sCJD.
Comment. Intravital diagnosis of sCJD can be given in a non-typical case, only if the patient is thoroughly examined and we take into consideration psychiatric and cognitive disturbances other than those which are typical for elderly patients. sCJD should always be considered when dementia signs worsen rapidly alongside with neurological and psychotic symptoms.