Aim. In the paper the treatment of spasticity with traditional pharmacological methods, i.e. phenol and ethanol injections was discussed.
Review. Spasticity is one of the most common and important problems in neurology, since the degree of spasticity may reflect the severity of disability in neurological patients with the upper motor neuron injury (due to stroke, multiple sclerosis, or trauma). Phenol and ethanol are the long-lasting local blocking agents used traditionally to treat spasticity.
Conclusions. Irrespective of clinical advantages, the main problems with this kind of treatment include correct patient selection, appropriate selection of involved muscles, and drawbacks related to unpleasant side effects (painful injections, chronic pain, and dysthesias).