Background. Metoclopramide, a drug widely used in common gastro-intestinal disturbances, shows also a dopaminolytic activity.
Case report. A 40-year-old woman treated with mianserine for depression, began receiving metoclopramide prescribed by a general practitioner to relieve dyspepsia. Within a week of the drug administration she developed dystonic-dyskinetic symptoms affecting the tongue and lips.
Commentary. Adverse side effects and complications of popular drugs (used also in self-treatment) are not commonly known. The report also sheds light on the difficulty in communication between physicians treating the same patient for different diseases.