2007 issue 3


Volume 16, issue 3

Review article

Sleep disorders in patients with multiple sclerosis

Piotr Koppa1, Jacek Losy2,3, Wojciech Kozubski4
1. Oddział Kliniczny Neurologii Samodzielnego Publicznego Szpitala Klinicznego nr 2 w Poznaniu
2. Zakład Neuroimmunologii Klinicznej Katedry Neurologii Akademii Medycznej w Poznaniu
3. Zespół Badawczo-Leczniczy Chorób Neuroimmunologicznych Instytutu Medycyny Doświadczalnej i Klinicznej Polskiej Akademii Nauk
4. Katedra i Klinika Neurologii Akademii Medycznej w Poznaniu
Postępy Psychiatrii i Neurologii 2007; 16 (3): 251-255
Keywords: multiple sclerosis, sleep disorders, polisomnography, magnetic resonance imaging


Objectives. Among patients suffering from multiple sclerosis (MS) various sleep disorders can be seen, often more than one and in different configurations. The disorders can occur at every stage of the disease, and even precede its first symptoms.
Review. The type of sleep disorders depends on the localisation of lesions in the central nervous system, and on the presence of other symptoms and syndromes in the course of MS (e.g. chronic fatigue syndrome, depression syndrome, nycturia).
The most common sleep disorders among MS patients are: insomnia, limb movement disorders during sleep, nocturnal breath disorders, narcolepsy and REM sleep behaviour disorders. Factors that may influence the quality of sleep include pain, nycturia, depression, drug side-effects, location of demyelination lesions and progression of the disease.
Conclusions. An attempt was made in the paper to draw attention to sleep disorders, since they are an important and often underestimatedproblem in SM patients.

Address for correspondence:
Dr Piotr Koppa
Os. Powstań Narodowych 1127, 61-213 Poznań
e-mail: piotr-koppa@wp.pl