Objectives. To describe a diagnostically challenging case of a 53-year-old female patient with depression symptoms and complex cogni-tive dysfunction.
Case report. Despite antidepressant treatment administered to the patient for three years, she displayed mood disorders and a gradual cognitive deterioration. A detailed diagnostic examination including neuropsychological assessment indicated that her symptoms wereprobably due to a vascular dementing process, and that the mood disorders were of reactive character. Antidepressants were replaced with apro-cognitive treatment and supplemented with psycho-corrective interventions appropriate to the patient 's individual needs, which provided good results.
Commentary. The case suggests that in patients resistant to treatment, presenting with a complex clinical picture and mixed etiology, diagnostic and therapeutic cooperation of a multi-specialist team is needed.