Objective. A case of acute non-allergic reaction following penicillin administration is described.
Case report. The major symptoms included dyspnoea, chest constriction, palpitations, and strong fear of death. The symptoms developed within less than 20 seconds from the injection and disappeared after about 15 minutes. The incident initiated a long-term anxiety disorder accompanied by somatic symptoms resembling the primary reaction to penicillin.
Commentary. A possibility of long-term sequelae of an acute reaction to medication should always be taken into account. Such side effects may severely impair the patient's psychosomatic condition and affect his/her quality of life.